Reportable Diseases

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Reportable Cancer List DX 10/2018 or later

REPORTABLE CASES – MISSISSIPPI

For cases diagnosed 10/1/2018 and after

The following lists are intended to assist you, as the reporter, in identifying the reportable neoplasms for your facility. Any reportable neoplasms diagnosed on or after January 1, 1996 should be reported to the Mississippi Cancer Registry.

REPORTABLE NEOPLASMS

  • Malignant neoplasms (exclusions noted below)
  • Benign and borderline neoplasms of the central nervous system (Cases diagnosed on or after January 1, 2004)
  • Pilocytic/juvenile astrocytoma listed as 9421/1 in ICD-O-3, is reportable, and should be coded to 9421/3.
  • Squamous intraepithelia l neoplasia grade III of vulva [VIN], vagina [VAIN], and anus [AIN] beginning with 2001 cases.
  • Carcinoid, NOS of the appendix is reportable and should be coded 8240/3 (Cases diagnosed on or after January 1, 2015)
  • Gastrointestinal Stromal Tumor (GIST), NOS with multiple tumor foci and/or metastasis to lymph nodes or distant sites.
  • Thymoma, NOS with multiple tumor foci and/or metastasis to lymph nodes or distant sites.
  • Malignant GIST and malignant thymomas
  • Solid pseudopapillary neoplasm of the pancreas (8452/3) (Cases diagnosed on or after January 1, 2015)
  • Cystic pancreatic endocrine neoplasm (CPEN) (8150/3), unless the tumor is specified as a neuroendocrine tumor, grade 1 (assign code 8240/3) or neuroendocrine tumor, grade 2 (assign code 8249/3) (For cases diagnosed January 1, 2015 or later)
  • Laryngeal intraepithelia l neoplasia, grade III (LINIII) (8077/2) (C320-C329) (For cases diagnosed January 1, 2015 or later)
  • Squamous intraepithelia l neoplasia, grade III (SIN III) (8077/2), except cervix and skin (For cases diagnosed January 1, 2015 and later)
  • Mature teratoma of the testes in adults (9080/3) (For cases diagnosed January 1, 2015 and later)

NON-REPORTABLE NEOPLASMS

  • Basal and squamous cell carcinomas of the skin (ICD-O-3 Histologies 8090-8110)
  • Epithelial carcinomas of the skin (ICD-O-3 Histologies 8010-8046)
  • Papillary and squamous cell carcinomas of the skin (ICD-O-3 Histologies 8050-8084)
  • Malignant neoplasms, NOS of the skin (ICD-O-3 Histologies 8000-8005)
  • Carcinoma in-situ of the cervix
  • Intraepithelial neoplasms of the cervix (ICD-O-3 Histology 8077/2) or prostate (ICD-O-3 Histology 8148/2)
  • Borderline cystadenomas (ICD-O-3 Histologies 8442, 8451, 8462, 8472, 8473), of the ovaries with behavior code "1" are not collected as of January 1, 2001
  • Cyst, brain or CNS tumor that does not have an ICD-O-3 code as of January 1, 2004
  • Gastrointestinal Stromal Tumor (GIST), NOS that are not stated to be malignant and are a single tumor with no metastasis to nodes or distant sites
  • Thymoma, NOS that are not stated to be malignant and are a single tumor with no metastasis to nodes or distant sites
  • Severe dysplasia of any site including the Gastrointestinal There must be a statement that this is carcinoma in situ to be reportable.
  • Mature teratoma of the testes in prepubescent children (9080/0)

AMBIGUOUS TERMINOLOGY

Terms That Constitute a Diagnosis**Terms That Do Not Constitute aDiagnosis
Apparent(ly)Cannot be ruled out
Appears toEquivocal
Comparable withPossible
Compatible withPotentially malignant
Consistent withQuestionable
Favor(s)Rule out
Malignant appearingSuggests
Most likelyWorrisome
Presumed 
Probable 
Suspect 
Suspicious 
Typical of 
Tumor (beginning with 2004 diagnosis andonly for C70.0-C72.9, C75.1-C75.3) 
Neoplasm (beginning with 2004 diagnosisand only for C70.0-C72.9, C75.1-C75.3) 

** Do not substitute synonyms such as "supposed" for "presumed" or "equal" for "comparable." Do not substitute "likely" for "most likely." Use on the exact words on the list.

Exceptions:

  • If a cytology is reported using any ambiguous term, do not interpret it as a diagnosis of cancer. Abstract the case only if a positive biopsy or a physician’s clinical impression of cancer supports the cytology
  • Genetic findings in the absence of pathologic or clinical evidence of reportable disease are indicative of risk only and do not constitute a diagnosis.

COMPREHENSIVE ICD-10-CM CASEFINDING CODE LIST FOR REPORTABLE TUMORS

ICD-10-CM CodesExplanation of Codes
C00._-C43._,C4A._, C45._-C48._, C49._ - C96._Malignant neoplasms (excluding category C44 and C49.A), stated or presumed to be primary (of specified site) and certain specified histologies1

NEW for 2018:

C96.20 Malignant mast cell neoplasm, unspecified

C96.21 Aggressive systemic mastocytosis

C96.22 mast cell sarcoma

C96.29 Other malignant cell neoplasm
C44.00, C44.09Unspecified/other malignant neoplasm of skin of lip
C44.10_, C44.19_Unspecified/other malignant neoplasm of skin of eyelid
C44.20_, C44.29_Unspecified/other malignant neoplasm skin of ear and externalauricular canal
C44.30_, C44.39_Unspecified/other malignant neoplasm of skin of other/unspecified parts of face
C44.40, C44.49Unspecified/other malignant neoplasm of skin of scalp & neck
C44.50_, C44.59_Unspecified/other malignant neoplasm of skin of trunk
C44.60_, C44.69_Unspecified/other malignant neoplasm of skin of upper limb, incl. shoulder
C44.70_, C44.79_Unspecified/other malignant neoplasm of skin of lower limb, including hip
C44.80, C44.89Unspecified/other malignant neoplasm of skin of overlapping sites of skin
C44.90, C44.99Unspecified/other malignant neoplasm of skin of unspecified sites of skin
C49.A_Gastrointestinal Stromal Tumors

Note: GIST is only reportable when it is malignant (/3). GIST, NOS (not stated whether malignant or benign) is a /1 and is not reportable.
D00._ – D09._In-situ neoplasms (Note: Carcinoma in situ of the cervix (CIN III-8077/2) and Prostatic Intraepithelial Carcinoma (PIN III-8148/2) are not reportable).
D18.02Hemangioma of intracranial structures and any site
D18.1Lymphangioma, any site (Note: Includes Lymphangiomas of Brain, Other parts of nervous system and endocrine glands, which are reportable)
D32._Benign neoplasm of meninges (cerebral, spinal and unspecified)
D33._Benign neoplasm of brain and other parts of central nervous system
D35.2 - D35.4Benign neoplasm of pituitary gland, craniopharyngeal duct and pineal gland
D42._, D43._Neoplasm of uncertain or unknown behavior of meninges, brain, CNS
D44.3 – D44.5Neoplasm of uncertain or unknown behavior of pituitary gland, craniopharyngeal duct and pineal gland
D45Polycythemia vera (9950/3)
D46._Myelodysplastic syndromes (9980, 9982, 9983, 9985, 9986, 9989,9991, 9992)
D47.1Chronic myeloproliferative disease (9960/3, 9963/3)
D47.3Essential (hemorrhagic) thrombocythemia (9962/3)
D47.4Osteomyelofibrosis (9961/3)

Includes: Chronic idiopathic myelofibrosis, Myelofibrosis (idiopathic) (with myeloid metaplasia), myelosclerosis (megakaryocytic) with myeloid metaplasia), secondary myelofibrosis in myeloproliferative disease
D47.Z_Neoplasm of uncertain behavior of lymphoid, hematopoietic and related tissue, unspecified (9960/3, 9970/1, 9931/3)
D47.9Neoplasm of uncertain behavior of lymphoid, hematopoietic and related tissue, unspecified (9931/3)
D49.6, D49.7Neoplasm of unspecified behavior of brain, endocrine glands and other CNS
R85.614Cytologic evidence of malignancy on smear of anus
R87.614Cytologic evidence of malignancy on smear of cervix
R87.624Cytologic evidence of malignancy on smear of vagina

1 Note: Pilocytic/juvenile astrocytoma M-9421 moved from behavior /3 (malignant) to /1 (borderline malignancy) in ICD-O-3. However, these cases should be reported and behavior coded as /3 (malignant).

SUPPLEMENTAL CASEFINDING LIST TO BE SCREENED FOR REPORTABLE CONDITIONS

Cases with the following codes should be screened as time allows. Experience has shown that use of this supplemental list increases casefinding for benign brain and CNS, hematopoietic neoplasms and other reportable diseases

ICD-10-CM CodesExplanation of Codes
B20Human immunodeficiency virus [HIV] disease with other diseases

Note: Excludes HIV with malignancy (B21), see reportable list
B97.33, B97.34,B97.35Human T-cell lymphotrophic virus, ( type I [HTLV-1], type II[HTLV-II], type 2 [HIV 2]) as the cause of diseases classified elsewhere
B97.7Papillomavirus as the cause of diseases classified elsewhere
C44.01, C44.02Basal/squamous cell carcinoma of skin of lip
C44.11_, C44.12_Basal/squamous cell carcinoma of skin of eyelid
C44.21_, C44.22_Basal/squamous cell carcinoma of skin of ear and externalauricular canal
C44.31_, C44.32_Basal/squamous cell carcinoma of skin of other and unspecified parts of face
C44.41, C44.42Basal/squamous cell carcinoma of skin of scalp and neck
C44.51_, C44.52_Basal/squamous cell carcinoma of skin of trunk
C44.61_, C44.62_Basal/squamous cell carcinoma of skin of upper limb, includingshoulder
C44.71_, C44.72_Basal/squamous cell carcinoma of skin of lower limb, includinghip
C44.81, C44.82Basal/squamous cell carcinoma of skin of overlapping sites of skin
C44.91, C44.92Basal/squamous cell carcinoma of skin of unspecified sites of skin
D10._ – D31._,D34, D35.0, D35.1, D35.5_ D35.9, D36._Benign neoplasms (see "must collect" list for reportable benignneoplasms)

Note: Screen for incorrectly coded
D3A._Benign carcinoid tumors
D37._ – D41._Neoplasms of uncertain or unknown behavior (see "must collect" list for reportable neoplasms of uncertain or unknown behavior)

Note: Screen for incorrectly coded malignancies
D44.0 – D44.2,D44.6-D44.9Neoplasm of uncertain or unknown behavior of other endocrine glands (see "must collect" list for D44.3-D44.5)

Note: Screen for incorrectly coded malignancies
D47.01Cutaneous mastocytosis (9740/1)Note: Effective 10/1/2017
C47.09Other mast cell neoplasms of uncertain behavior

Note: Effective 10/1/2017
D47.2Monoclonal gammopathy

Note: Screen for incorrectly coded Waldenstrom’s macroglobulinemia
D47.Z2Castleman disease
D48._Neoplasm of uncertain behavior of other and unspecified sites
D49.0 – D49.9Neoplasm of unspecified behavior (except for D49.6 and D49.7)
D61.1Drug-induced aplastic anemia (also known as "aplastic anemia due to antineoplastic chemotherapy")
D61.810Anemia due to antineoplastic chemotherapy
D61.82Myelophthisis
D63.0Anemia in neoplastic disease
D64.81Anemia due to antineoplastic chemotherapy
D69.49, D69.59,D69.6Other thrombocytopenia

Note: Screen for incorrectly coded thrombocythemia
D70.1Agranulocytosis secondary to cancer chemotherapy
D72.1Eosinophilia (Note: Code for eosinophilia (9964/3). Not every caseof eosinophilia is a malignancy. Reportable Diagnosis is "Hypereosonophilic syndrome.")
D75.81Myelofibrosis (note: this is not primary myelofibrosis [9961/3])
D76._Other specified diseases with participation of lymphoreticular andreticulohistiocytic tissue
D89.0, D89.1Other disorders involving the immune mechanism, not elsewhere classified

Note: Review for miscodes
D89.4_Mast cell activation syndrome and related disorders

Note: effective 10/1/2016
E08Diabetes mellitus due to underlying condition
E31.2_Multiple endocrine neoplasia [MEN] syndromes
E34.0Carcinoid syndrome
E83.52Hypercalcemia
E88.09Other disorders of plasma-protein metabolism, not elsewhereclassified
E88.3Tumor lysis syndrome (following antineoplastic chemotherapy)
G13.0Paraneoplastic neuromyopathy and neuropathy
G13.1Other systemic atrophy primarily affecting central nervous systemin neoplastic disease
G32.8Other specified degenerative disorders of nervous system in diseases classified elsewhere
G53Cranial nerve disorders in diseases classified elsewhere

Note: Code first underlying neoplasm (C00-D49)
G55Nerve root and plexus compressions in diseases classified elsewhere

ICD-10-CM Coding instruction note: code also underlying disease, such as neoplasm (C00-D49)
G63Polyneuropathy in diseases classified elsewhere
G73.1Lambert-Eaton syndrome in neoplastic disease
G89.3Neoplasm related pain (acute)(chronic)
G99.2Myelopathy in disease classified elsewhere
H47.42Disorders of optic chiasms in (due to) neoplasm
H47.52_Disorders of visual pathways in (due to) neoplasm
H47.63_Disorders of visual cortex in (due to) neoplasm
J34.81Nasal mucositis (ulcerative)
J91.0Malignant pleural effusion
J93.12Secondary spontaneous pneumothorax
K12.31Oral mucositis (ulcerative) due to antineoplastic therapy
K12.33Oral mucositis (ulcerative) due to radiation
K22.711Barrett’s esophagus with high grade dysplasia
K62.7Radiation proctitis
K62.82Dysplasia of anus (AIN I and AIN II)
K92.81Gastrointestinal mucositis (ulcerated) (due to antineoplastictherapy)
M36.0Dermato(poly)myositis in neoplastic disease
M36.1Arthropathy in neoplastic disease
M84.5_Pathologic fracture in neoplastic disease
M90.6_Osteitis deformans in neoplastic disease
N42.3Dysplasia of prostate (PIN I and PIN II)
N76.81Mucositis (ulcerative) of vagina or vulva
N87._Dysplasia of cervix uteri (CIN I and CIN II)
N89.0, N89.1,N89.3Vaginal dysplasia (VIN I and VIN II)
N90.0, N90.1,N90.3Vulvar dysplasia (VAIN I and VAIN II)
O01._Hydatidiform mole

Note: Benign tumor that can become malignant. If malignant, report as Choriocarcinoma (9100/3, ) malignancy code in the C00- C97 range
O9A.1_Malignant neoplasm complicating pregnancy, childbirth and thepuerperium
P04.11Newborn affected by maternal antineoplastic chemotherapy

Note: Effective 10/1/2018
P04.12Newborn affected by maternal cytotoxic drugs

Note: Effective 10/1/2018
Q85.0_Neurofibromatosis (nonmalignant) (9540/1)Note: Neurofibromatosis is not cancer. These tumors can beprecursors to acoustic neuromas, which are reportable
R18.0Malignant ascites
R53.0Neoplastic (malignant) related fatigue
R59._Enlarged lymph nodes
R85.6_Abnormal findings on cytological and histological examination ofdigestive organs
R87.61_, R87.62_Abnormal findings on cytological/histological examination offemale genital organs
R92._Abnormal findings on diagnostic imaging of breast
R97._Abnormal tumor markers
T38.6_Poisoning by antigonadotropins, antiestrogens, antiandrogens, notelsewhere classified
T38.8_, T38.9_Poisoning by hormones and their synthetic substitutes
T45.1_Poisoning by, adverse effect of and under dosing of antineoplasticand immunosuppressive drugs
T45.8_, T45.9_Poisoning by primary systemic and hematological agent, unspecified
T66Unspecified effects of radiation
T80.1Vascular complications following infusion, transfusion andtherapeutic injection
T80.2_Infections following infusion, transfusion and therapeutic injection
T80.810Extravasation of vesicant antineoplastic chemotherapy
T80.818Extravasation of other vesicant agent
T86.0Complications of bone marrow transplant
Y63.2Overdose of radiation given during therapy
Y84.2Radiological procedure and radiotherapy as the cause of abnormalreaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
Z03.89Encounter for observation for other suspected diseases andconditions ruled out
Z08Encounter for follow-up examination after completed treatment for malignant neoplasm
Z12._Encounter for screening for malignant neoplasms
Z13.0Encounter of screening for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Z15.0Genetic susceptibility to malignant neoplasm
Z17.0, Z17.1Estrogen receptor positive and negative status
Z40.0_Encounter for prophylactic surgery for risk factors related tomalignant neoplasms
Z42.1Encounter for breast reconstruction following mastectomy
Z48.290Encounter for aftercare following bone marrow transplant
Z48.3Aftercare following care for neoplasm
Z51.0Encounter for antineoplastic radiation therapy
Z51.1_Encounter for antineoplastic chemotherapy and immunotherapy
Z51.5, Z51.89Encounter for palliative care and other specified aftercare
Z79.81_Long term (current) use of agents affecting estrogen receptors andestrogen levels
Z80._Family history of primary malignant neoplasm
Z85._Personal history of malignant neoplasm
Z86.0_, Z86.01_,Z86.03Personal history of in situ and benign neoplasms and neoplasms ofuncertain behavior
Z92.21, Z29.23,Z92.25. Z92.3Personal history of antineoplastic chemotherapy, estrogen therapy, immunosuppression therapy or irradiation (radiation)
Z94.81, Z94.84Bone marrow and stem cell transplant status